Understood as an industry concept recently proposed that encompasses the main technological innovations of the fields of automation, control and information technology applied to the manufacturing processes, Industry 4.0 is a real challenge for today’s businesses. Indeed, from cyber-physical systems, Internet of Things and Internet Services, the pro-duction processes tend to become increasingly efficient, autonomous and customizable. The relationship with costumers is also more effective. In other words, the availability of real-time data enables organizations to offer more personalized products and customized solutions, which usu-ally originates significantly higher margins than mass-manufacturing offers. Taking in mind these changes and implications in organizations, the present book, entitled Industry 4.0 – Challenges, Trends, and Solutions in Management and Engineering, looks to provide a support to academ-ics, researchers and practitioners, as well as all to those who operate in the Management and Engineering fields and need to deal with the rapid pace of digitization in industry today. Becoming more active in Industry 4.0, these organizations see their benefits go far beyond extending the digital reach or selling new types of products and services. Industry 4.0 will establish these organizations, their employees as well as their total ecosystem of stakeholders, namely, suppliers, partners, distributors and customers as a complete interconnected and integrated digital network, linked to other networks around the world.